Increased hydrogel stability for immuno(histo)chemistry after culture

The crosslinking approach. First the fibrous gel is formed, then the crosslinks are formed selectively in the bundles. Source: Noviocell

Noviogel hydrogels can be crosslinked after cell or organoid culture without loss of the reversible thermosensitive property during culture

Because of the reversible thermosensitive behavior of Noviogel, some researchers experience difficulties in using the hydrogel for immune staining. By using a crosslinker after culture, the properties of Noviogel are still intact like ease of use in cell passaging and retrieval of cells for other downstream applications. The solution was reported in this latest Nature Communication paper of the group of Paul Kouwe.



   Read it on the NOVIOCELL website.