Publications

2018

      • The force-dependent mechanisms of DnaK-mediated mechanical folding; Perales-Calvo, J., Giganti, D., Stirnemann, G., Garcia-Manyes, S. Science Advances February 2018; DOI: 10.1126/sciadv.aaq0243

     

      • Molecular clutch drives cell response to surface viscosity; Bennett, M., Cantini, M., Reboud, J., Cooper, J. M., Roca-Cusachs, P. and Salmeron-Sanchez, M. Proceedings of the National Academy of Sciences, January 2018; DOI: https://doi.org/10.1073/pnas.1710653115

     

2017

      • Force loading explains spatial sensing of ligands by cells; Roger Oria, Tina Wiegand, Jorge Escribano, Alberto Elosegui-Artola, Juan Jose Uriarte, Cristian Moreno-Pulido, Ilia Platzman, Pietro Delcanale, Lorenzo Albertazzi, Daniel Navajas, Xavier Trepat, José Manuel García-Aznar, Elisabetta Ada Cavalcanti-Adam and Pere Roca-Cusachs. Nature, December 2017; DOI: 10.1038/nature24662

     

      • Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores; Alberto Elosegui-Artola, Ion Andreu, Amy E. M. Beedle, Ainhoa Lezamiz, Marina Uroz, Anita J. Kosmalska, Roger Oria, Jenny Z. Kechagia, Palma Rico-Lastres, Anabel-Lise Le Roux, Catherine M. Shanahan, Xavier Trepat, Daniel Navajas, Sergi Garcia-Manyes and Pere Roca-Cusachs. Cell, Nov. 2017; DOI: https://doi.org/10.1016/j.cell.2017.10.008

     

      • Long-lived force patterns and deformation waves at repulsive epithelial boundaries; Pilar Rodríguez-Franco, Agustí Brugués, Ariadna Marín-Llauradó, Vito Conte, Guiomar Solanas, Eduard Batlle, Jeffrey J. Fredberg, Pere Roca-Cusachs, Raimon Sunyer and Xavier Trepat.  Nature Materials, Sept. 2017; DOI: 10.1038/NMAT4972

     

      • Membrane tension controls adhesion positioning at the leading edge of cells; Bruno Pontes, Pascale Monzo, Laurent Gole, Anabel-Lise Le Roux, Anita Joanna Kosmalska, Zhi Yang Tam, Weiwei Luo, Sophie Kan, Virgile Viasnoff, Pere Roca-Cusachs, Lisa Tucker-Kellogg, and Nils C. Gauthier. JCB: Article, July 2017; DOI: 10.1083/jcb.201611117

     

      • Binding of ZO-1 to α5β1 integrins regulates the mechanical properties of α5β1–fibronectin links; Víctor González-Tarragó, Alberto Elosegui-Artola, Elsa Bazellières, Roger Oria, Carlos Pérez-González and Pere Roca-Cusachs . Mol Biol Cell. July 2017; DOI:  10.1091/mbc.E17-01-0006

     

      • Quantifying forces in cell biology; Roca-Cusachs, P., Conte, V. and Trepat, X. Nature Cell Biology, June 2017; DOI:10.1038/ncb3564

     

      • NatB-mediated protein N-α-terminal acetylation is a potential therapeutic target in hepatocellular carcinoma. Neri, L., Lasa, M., Elosegui-Artola, A., D’Avola, D., Carte, B., Gazquez, C., Alve, S., Roca-Cusachs, P., Iñarrairaegui, M., Herrero, J., Prieto, J., Sangro, B. and Aldabe, R. Oncotarget, June 2017; DOI: 10.18632/oncotarget.17332

     

      • Amoebae as mechanosensitive tanks. Elosegui-Artola, A. and Roca-Cusachs, P. Biophysical Journal, June 2017; DOI: https://doi.org/10.1016/j.bpj.2017.05.020

     

      • A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion. Labernadie, A., Kato, T., Brugués, A., Serra-Picamal, X., Derzsi, S., Arwert, E., Weston, A., González-Tarragó, V., Elosegui-Artola, A., Albertazzi, L., Alcaraz, J., Roca-Cusachs, P., Sahai, E. and Trepat, X. A Nature Cell Biology, February 2017; DOI:10.1038/ncb3478