King’s College London Prof. Sergi Garcia-Manyes has been featured in Chemistry World, on its latest article on mechanochemistry, “Introducing mechanochemistry”. In the article, Garcia-Manyes explains how they induce chemical reactions by applying forces with an AFM on single chemical bonds in a molecule. This reaction can trigger the assembly of several molecules into a protein and its folding without the use of enzymes.
Xavier Trepat is one of six featured in Nature Physics’ latest ‘Insight’ issue, ‘The Physics of Living Systems’, in which all the articles have been co-authored by a physicist and a biologist.
Penned together with collaborator Erik Sahai from London’s Francis Crick Institute, Xavier’s article, ‘Mesoscale physical principles of collective cell organization’, reviews recent evidence showing that cell and tissue dynamics are governed by mesoscale physical principles – force, density, shape, adhesion and self-propulsion.
Noviogel hydrogels can be crosslinked after cell or organoid culture without loss of the reversible thermosensitive property during culture
Because of the reversible thermosensitive behavior of Noviogel, some researchers experience difficulties in using the hydrogel for immune staining. By using a crosslinker after culture, the properties of Noviogel are still intact like ease of use in cell passaging and retrieval of cells for other downstream applications. The solution was reported in this latest Nature Communication paper of the group of Paul Kouwe.
Mind the Byte’s CEO Alfons Nonell and Scientific Director Melchor Sanchez have taken part of the Pint of Science Festival, a global science outreach event taking place simultaneously in 21 countries.
The Pint of Science festival on 14th-16th May aims to deliver interesting, fun and relevant talks on the latest scientific research by the people who carry it out – in the pub!
On 15th May Alfons gave a talk, “Drug Design with Artificial Intelligence” at BlackLab Brewhouse bar on Plaça Pau Vila. At the same time – taking a different stage, though -, Melchor also spread the word on the same topic at the D9 bar on Carrer de Pallars.
Pint of Science, which was established by a community of postgraduate and postdoctoral researchers at Imperial College in 2012, takes place annually over three days simultaneously in pubs in 21 countries.
Read more on the Pint of Science website: here and here.
IBEC group leader and member of Mechanocontrol consortium Xavier Trepat has been elected as a Member of EMBO, the European Molecular Biology Organisation.
EMBO’s members are 1,800 leading researchers that promotes excellence in the life sciences, and new ones are elected annually in recognition of their contributions to scientific excellence. Of the 62 researchers from 24 countries to receive membership this year, Xavier is one of the only two researchers in Spain.
The Integrative Cell and Tissue Dynamics group leader is IBEC’s first full EMBO Member, and one of just 79 based in Spain. In 2016 IBEC group leader Pere Roca-Cusachs was accepted into the EMBO Young Investigator Programme.
Today we echo an interesting post by Noviocell which summarizes the key factors to best re create the cell environment with a cell culture model.
3D culture in naturally derived hydrogels such as Matrigel or collagen matrices has shown to drive cellular self-organization and complex morphogenetic processes to result in sophisticated in vitro models. However, current methods mostly rely on natural derived materials that fail to enable fine and controlled manipulation of matrix parameters and culture conditions.
During this month, at IBEC we had several workshops on mechanobiology. With Escola Roig Tessàlia, on 7th March, our students Ariadna and Macià (from Xavier Trepat’s group) have explored how cells exert forces and the students have measured them and created a cell membrane model. Later, on the 14th, escola Nazaret also visited us and this time the workshop was imparted by Xarxa (from Pere Roca-Cusachs’ group) and Ariadna.
Yesterday, CataloniaBio & HealthTech awarded the 2018 Biosuccess Award recognising the most important business milestones in biomedicine and health in Catalonia to Anaconda Biomed and Mind the Byte. The ceremony took place during the CataloniaBio & HealthTech Gala Dinner at the Museu Marítim of Barcelona, featuring president of CataloniaBio & HealthTech, Jaume Amat; CEO of ACCIÓ, Joan Romero; director general for Research and Innovation in Health, Albert Barberà; and over 200 entrepreneurs, executives and investors from the sector.
This was the moment that IBEC group leader Pere Roca-Cusachs received the City of Barcelona Award for the life sciences from Barcelona mayor Ada Colau.
Pere won the prize for his study in Cell last year which identified a mechanism by which tissue rigidity regulates cell survival and proliferation, as well as its implications in diseases such as cancer and liver and lung fibrosis. The ceremony took place last night in the city council’s Saló de Cent, where the twenty winners of this year’s prizes, now in their 17th edition, were congratulated by Ms. Colau and Culture Commissioner Joan Subirats.